Alok adds warning : Doctors easily prescribe Wysolone / Prednisolone or other steroids. But no one in writing gives precautions, no doc. educates family of patients , doctors must also put patient on regular pathological tests to keep in check serious changes if happening. The medicines delivered / handed over by chemists comes without literature. Literature must be made mandatory as that contains lots of info on the product and patient must know all that before starting the medicine.In medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment. Contraindication is the opposite of indication, which is a reason to use a certain treatment. In India we go to different doctors for different ailments. Both independently treat a patient. They often give medicine which are contraindicated but the one doc does not know if patient is being treated by another doc for another ailment with a medicine which is contraindicated. Docs have no time to take full history. Actually there must be trained receptionist/ assistant to all specialists who must take detailed history, allergies if any , which are the medications patient is already on, and so on. But busiest and richest docs too do not spend on assistants. So called ultra modern Ambani hospital also does not provide assistants to senior specialists so they prescribe without going in details.In Sankara Nethralaya, Chennai doctors enter everything ( history, reports, prognosis, recommendations, etc online and as u come of of doctors chamber u r handed over a computer printout in hand which gives clear cut info of your status as u entered and advise and follow up details. The assistants to doctors are trained and knowledgeable. Here in Ambani docs still hand write , and give incomplete unreadable paper in hand.An appropriate Law should also be framed where doctors must given in writing parhej ( what food and medicines must be avoided ) and what must be taken as supportive food. Ayurvedic doctors in India follow this practice. There are some allopathic doctors who advise necessary fruits, moong dal , mosambi, 20 min. yoga, walk etc and so on. This is because many thing patient does not get or in many activity patient needs support of family etc which if he is officially prescribed then patients/ family takes it seriously or else good meal / physical activity is forgotten. Dr Panda of Asian Heart has developed a full regime of do's and donts and is officially given to patients and family counseling too is being done there. We see several of his heart patients now participate in marathon. Asian heart also has yahoogroup of patients who regularly communicate with each other on their common issues.
Surendra Says:
My younger brother aged 35 years had a problem of double vision in left eye due to nerve damage and as per doctor advise, he used wysolone tablets 120mg per day along with other medicines for 45 days.
The doctor did not told us the side effect of wysolone and precautions which we have to take while using wysolone. We don't know that wysolone is a steroid. Due to this drug, my brother got side effects such as round face, double chin, rashes on all over body and heavy hungry. His eye problem is reduced in these 45 days. after 45 days, the doctor reduced wysolone drug by 80mg, 60mg,40mg like that per day. After 3days, he got problems of loose motions and vomtings and he became very weak. I took him to hospital . Doctors told that he is suffering with lack of immunity power due to steroid intake. After that he developed multi organ failure such as ARDS(Accute Respiratory Dissiminate Syndrom) or accute lung ingury, brain failure, liver damage, kidnies damage, shortage of blood cells(plasma) etc. All this problems he got due to immuno suppression secondary to steroid intake. He treated on mechanical ventilator for 12 days. It is a costly treatment for us and we expend 8 lacs for his treatment by borrow money from friends, relatives and bank. After putting all efferts, he died and leave us in sadness.
if the doctor tell us about the side effect of wysolone, my brother will live with us and my parents don't get depression at this age.
I request all of you that please take care while using of wysolone. This drug will eat immunity power and will cause so many problems.
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Rao HSG Says:
One year back I have been diagnosed for Ocular myasthania.. & was advised wysolone -20 mg x 3 daily, Gravitor 60mg x 3 daily... After taking this four months OM Came to control.. When my Dr. Replaced the medicine to ozotherapine within two weeks, I got jaundice & I was hospitalized for a week... During that period my bilirubin content went up to 37.... SGPT & SGOT also shooted up to 700+ ..... During that time wysolone & Gravitor was stopped... After two months of jaundice I had double vision problem... for which I underwent plasmapheresis process..which costed all most two lakhs.. Now my double vision problem is solved..but again my dr.suggested to continue wysolone20 x2, & gravitor60 x 3 daily...& mucophenalyte-500mg x 2 daily... I also have double chin. Face is enlarged, rashes all over the body..frequent urination... Frequent stools...although double vision problem is solved.I am experiencing some problems with my left eye...when showed to eye specialist they told that LEye is in the initial stage of cataract...still my dr..advice me to continue the wysolone & Gravitor for few more months... I am really worried.. Is there any alternate medicine so that there shouldn't side effects.... Is there any treatment for my problem in homeopathy or Ayurvedic .....pl suggest
The doctor did not told us the side effect of wysolone and precautions which we have to take while using wysolone. We don't know that wysolone is a steroid. Due to this drug, my brother got side effects such as round face, double chin, rashes on all over body and heavy hungry. His eye problem is reduced in these 45 days. after 45 days, the doctor reduced wysolone drug by 80mg, 60mg,40mg like that per day. After 3days, he got problems of loose motions and vomtings and he became very weak. I took him to hospital . Doctors told that he is suffering with lack of immunity power due to steroid intake. After that he developed multi organ failure such as ARDS(Accute Respiratory Dissiminate Syndrom) or accute lung ingury, brain failure, liver damage, kidnies damage, shortage of blood cells(plasma) etc. All this problems he got due to immuno suppression secondary to steroid intake. He treated on mechanical ventilator for 12 days. It is a costly treatment for us and we expend 8 lacs for his treatment by borrow money from friends, relatives and bank. After putting all efferts, he died and leave us in sadness.
if the doctor tell us about the side effect of wysolone, my brother will live with us and my parents don't get depression at this age.
I request all of you that please take care while using of wysolone. This drug will eat immunity power and will cause so many problems.
https://in.answers.yahoo.com/question/index?qid=20110930103552AAGcfvz
actually there is no such documentation on the time it takes for the cure, no drug have specific time limit.
It is a steroid containing Prednisolone,
You may experience, increased appetite, indigestion or anxiety.
Alert your doctor if you experience any sudden weight gain, swelling of legs or arms, breathlessness, stomach pain, severe vomiting, black or thick stools, extreme tiredness, muscle weakness or unusual mood swings.
may also cause increased growth of hair on the face, muscle and bone ache, eyesight problems.
However, these side effects are usually not common and not a cause for concern, especially if you are taking WYSOLONE for a short period of time only.
More information you can get from
Wikipedia
http://en.wikipedia.org/wiki/Prednisolon...
MIMS
http://www.mims.com/India/patientmedicin...
It is a steroid containing Prednisolone,
You may experience, increased appetite, indigestion or anxiety.
Alert your doctor if you experience any sudden weight gain, swelling of legs or arms, breathlessness, stomach pain, severe vomiting, black or thick stools, extreme tiredness, muscle weakness or unusual mood swings.
may also cause increased growth of hair on the face, muscle and bone ache, eyesight problems.
However, these side effects are usually not common and not a cause for concern, especially if you are taking WYSOLONE for a short period of time only.
More information you can get from
Wikipedia
http://en.wikipedia.org/wiki/Prednisolon...
MIMS
http://www.mims.com/India/patientmedicin...
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http://en.wikipedia.org/wiki/Prednisolone
Adverse effects[edit]
Possible side-effects include fluid retention of the face (moon face, Cushing's syndrome), acne, constipation, and mood swings.
A lengthy course of prednisolone can cause bloody or black tarry stools from bleeding into the stomach (this requires urgent medical attention); filling or rounding out of the face; muscle cramps or pain; muscle weakness; nausea; pain in back, hips, ribs, arms, shoulders, or legs; reddish-purple stretch marks on arms, face, legs, trunk, or groin; thin and shiny skin; unusual bruising; urinating at night; rapid weight gain; and wounds that will not heal.
Prolonged use of prednisolone can lead to the development of osteoporosis which makes bones more fragile and susceptible to fractures. One way to help alleviate this side effect is through the use of calcium and vitamin D supplements.[9]
Prednisolone can cause increased blood sugar levels for diabetics.
Other effects include decreased or blurred vision, increased eye pressure, increased thirst, cataract formation, confusion, rare cases of dementia in otherwise-healthy elderly patients, and nervousness.
Loteprednol is an analog drug that has reduced adverse ocular effects.
Prednisolone may cause serious mental health problems, these affect around 5% who take such steroids.[10] Symptoms include:
- depression, including suicidal thoughts
- feeling high (mania) or mood swings
- anxiety
- insomnia
- difficulty in thinking / confusion
- memory loss
- visual, auditory or tactile hallucinations
- having strange and frightening thoughts, changing behaviour or having feelings of being alone
Nasal septum perforation and bowel perforation are also notable adverse effects that restrict steroids' use in some pathologic conditions.[11][12]
Withdrawal from prednisolone can be problematic after taking large doses or over more than two weeks.[13] This is caused by prednisolone inhibiting the natural production of corticosteroids in the "Hypothalamic-Pituitary-Adrenal Axis" (HPAA)[13]
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http://www.mims.com/India/drug/info/prednisolone/
| ndications | Listed in Dosage. |
| Dosage | Adult: PO Allergic and inflammatory disorders 5-60 mg/day, in 2-4 divided doses. Rheumatoid arthritis Initial: 5-7.5 mg/day, adjust dose if needed. Multiple sclerosis 200 mg/day for 1 wk, then 80 mg every other day for 1 mth. IV/IM Allergic and inflammatory disorders Given as Na phosphate ester: 5-60 mg prednisolone base/day. Ophth Conjunctivitis As 0.12 or 1% acetate susp: Instill 1-2 drops 2-4 times/day. Higher frequency may be used during the initial 24-48 hr. Re-evaluate if there is no improvement after 2 days of treatment. Otic Allergic and inflammatory conditions of the ear As 0.5 or 1% acetate or phosphate soln: Instill as directed. Intra-articular Joint inflammations As acetate: 5-25 mg. As phosphate: 2-30 mg. As terbutate:4-40 mg. Topical Rheumatoid arthritis As farnesylate: Apply to the affected area as necessary. Click to view prednisolone Dosage by Indications |
| Administration | Should be taken with food. |
| Overdosage | For action to be taken in the event of accidental overdose ... click to view prednisolone |
| Contraindications | Live vaccines; herpes simplex keratitis, systemic infections. |
| Special Precautions | Patients with hypothyroidism, cirrhosis, ulcerative colitis, CHF, convulsive disorders, thrombophlebitis, peptic ulcer, elderly. DM, hypertension, psychological disturbances, osteoporosis; pregnancy, lactation. Adrenal suppression and infection. May cause irreversible growth retardation, glaucoma, corneal perforation. Topical: Broken or infected skin. Not to be applied over large areas under occlusive dressings. |
| Adverse Drug Reactions | Cushing's syndrome and growth retardation in childn; osteoporosis, fractures. Peptic ulceration; glaucoma, cataracts; hyperglycaemia, pancreatitis; increased appetite, obesity. Topical: Thinning and atrophy, systemic absorption with prolonged use over large surface, broken skin or under occlusive dressing. Rash, allergic reactions, pruritus. Intradermal/Intralesional: Local hypopigmentation of hyperpigmented lesions. Ophthalmic: Raised IOP and reduced visual function. Potentially Fatal: Acute adrenal insufficiency precipitated by infection, trauma or surgery in patients on long-term therapy or following cessation of such therapy. CV collapse following rapid IV injection. |
| Drug Interactions | Increased requirement of insulin and oral hypoglycaemics. Actions blunted by barbiturates, phenytoin, rifampicin. Increased bioavailability with estrogens and oral contraceptives. Increases plasma salicylate levels. Increased risk of convulsions when used with ciclosporin, increased clearance by carbimazole or carbamazepine. Increased risk of GI bleeding and ulceration when used with NSAIDs. May decrease methotrexate clearance. |
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